Conservation interventions, such as eradicating feral invasive cats, rabbits or foxes, can lead to unintentional negative outcomes through chains of species interactions. For effective conservation management of ecosystems, we need to predict the outcomes before the intervention occurs. Modelling is a useful tool to make predictions about potential cascading outcomes and inform conservation decision-making. This can allow us to plan for potentially negative outcomes accordingly and suggest strategies to meet multi-species objectives. In this talk, I will discuss recent progress in the field and discuss applications of these methods, focusing on the effect of mammalian predators on ecosystem dynamics. In particular, I will discuss ecosystem models that estimate the impact of fox control on malleefowl populations, and how dingo and eastern quoll reintroduction could affect the recipient ecosystems.